Isolation of plasma membranes from bovine corpus luteum possessing adenylate cyclase, 125I-hCG binding and Na-K-ATPase activities.
نویسندگان
چکیده
Plasma membranes from bovine corpora lutea have been purified by sucrose density gradient centrifugation. The purified membranes, in addition to binding 1251-hCG, also possess hCGstimulated adenylate cyclase and Na-K-ATPase. The relative purification of 1251-hCG binding, adenylate cyclase and Na-KATPase on the basis of the specific activities in the whole homogenate were 7.8, 6.4 and 2.6, respectively. The presence of both the hormone sensitive adenylate cyclase and 1251-hCG binding activities suggest that these plasma membranes might possess the 'receptor' for gonadotropin.
منابع مشابه
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عنوان ژورنال:
- Biochemical and biophysical research communications
دوره 56 2 شماره
صفحات -
تاریخ انتشار 1974